PPT Slide

DISCUSSION AND CONCLUSIONS:

• Stimulation of 5-HT2A receptors appears to be

an integral component to the reinforcing effects

of MDMA, but not to those of cocaine.

• 5-HT2A receptors may be particularly important

in the reinforcing effects of (-)-MDMA.

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Why these antagonistic actions do not seem to extend to the reinforcing effects of cocaine is unclear.